Screening of immigrants in the UK for latent tuberculosis.
نویسندگان
چکیده
Evaluation of: Pareek M, Watson JP, Ormerod LP et al. Screening of immigrants in the UK for imported latent tuberculosis: a multicentre cohort study and cost-effectiveness analysis. Lancet Infect. Dis. 11(6), 435-444 (2011).Tuberculosis (TB) is a serious public health problem in the UK, and detection and prophylactic treatment of latent infection offers improved control. A recent study advocates the use of IFN-γ release assays to detect latent TB infection in immigrants to the UK under 35 years of age and suggests that such a program would be most cost effective if targeted at new entrants from high burden countries. We discuss these findings in the light of recently updated UK and European guidelines. We conclude that while action to contain TB in the UK is urgently needed, further evidence is required to assess the impact and cost-effectiveness of screening algorithms for latent infection.
منابع مشابه
Screening of immigrants in the UK for imported latent tuberculosis: a multicentre cohort study and cost-effectiveness analysis
BACKGROUND Continuing rises in tuberculosis notifications in the UK are attributable to cases in foreign-born immigrants. National guidance for immigrant screening is hampered by a lack of data about the prevalence of, and risk factors for, latent tuberculosis infection in immigrants. We aimed to determine the prevalence of latent infection in immigrants to the UK to define which groups should ...
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In the UK, tuberculosis is an urgent public health problem, particularly for immigrants and other socially deprived and vulnerable groups. London has the highest rate of tuberculosis of any western European capital. Although recently improved National Health Service tuberculosis services aimed at early diagnosis and initiatives to prevent transmission in hard-to-reach groups are in place, these...
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BACKGROUND Most UK tuberculosis (TB) cases occur in immigrants from high TB incidence areas, implicating reactivation of imported latent TB infection (LTBI). Strategies to identify and treat immigrant LTBI in primary care at the time of first registration (coded Flag-4) may be effective. METHODS This was an 11-year retrospective cohort study to evaluate effectiveness of LTBI screening in rece...
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NICE (National Institute for Health and Clinical Excellence) guidelines for new entrant tuberculosis (TB) screening recommend chest x ray (CXR) for immigrants from countries with TB incidence >40/10(5), and tuberculin skin test (TST) for people with normal CXR from very high TB prevalence countries. A revised screening policy using first-line QuantiFERON-TB Gold (QFT) in high risk immigrants wa...
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ورودعنوان ژورنال:
- Expert review of respiratory medicine
دوره 5 4 شماره
صفحات -
تاریخ انتشار 2011